manacles Get Printable Handwriting (man-a-cles) 3 syllables Learn It! Spelling Test Definition noun. a handcuff or fetter or shackle for the hand;verb. confine or restrain with or as if with handcuffs Example Sentence The manacles were tight around the pirate's wrists. Synonyms cuff; handcuff; fetter; shackle Antonyms loose; unrestrained Share with your friends: