invagination Get Printable Handwriting (in-vag-i-na-tion) 5 syllables Learn It! Spelling Test Definition noun. the process of folding or turning inward; n. - a condition in which a part of the body is folded or turned inward Example Sentence The invagination of the cell membrane allows substances to enter the cell. Synonyms folding; tucking; turning inward Antonyms expansion; unfolding Share with your friends: